HOW IT WORKS
Take quick free assessment
Tell us about your symptoms and medical history. We’ll let you know right away if the program could work for you.
Text with a doctor
Our text-based program puts doctors on your schedule. Get in touch whenever you want, from the privacy of home.
Get treatment shipped to you
If medication is prescribed, get it shipped directly to your door for free or pick it up from your local pharmacy.
Available in all 48 continental US states. Not available in Alaska or Hawaii.
K Health memberships are not insurance and exclude ancillary services (e.g., labs, equipment, cost of medication, etc). See Terms of Service.
What is Cymbalta?
Cymbalta is a serotonin and norepinephrine reuptake inhibitor (SNRI) antidepressant medication that was approved by the FDA for patient use for the treatment of depression in 2004. In 2007 it was approved by the FDA for the treatment of generalized anxiety disorder. It can also be used to treat diabetic neuropathy, fibromyalgia, chronic bone or muscle pain, and pain due to osteoarthritis.
In 2007 it was approved by the FDA for the treatment of generalized anxiety disorder. It can also be used to treat diabetic neuropathy, fibromyalgia, ongoing bone or muscle pain, and osteoarthritis.
Examples of other SNRI antidepressants include desvenlafaxine (Pristiq, Khedezla), and venlafaxine (Effexor).
Off-label, Cymbalta is also used to treat chemotherapy-induced peripheral neuropathy and stress urinary incontinence in both men and women.
Do you need a prescription for Cymbalta?
Yes, Cymbalta and its generic form, duloxetine, are only available by prescription.
It’s important to speak with your medical provider when undergoing treatment with Cymbalta, another SNRI, or any antidepressant. Like most antidepressants, Cymbalta may not be right for everyone. Which is why it’s important to take the medication only while under consistent supervision of a medical professional.
When speaking with a licensed medical provider about whether or not Cymbalta is right for you, your provider will evaluate your medical history, discuss your symptoms, and, if appropriate, prescribe you the medication.
Keep in mind that if this is your first time taking antidepressant medication, your provider may recommend starting treatment with a selective serotonin reuptake inhibitor, or SSRI, before trying Cymbalta or another SNRI.
How does Cymbalta work?
Cymbalta works by inhibiting serotonin and norepinephrine reuptake, two neurotransmitters in the brain. By doing this, Cymbalta combines two therapeutic mechanisms that can be effective at treating depression and anxiety.
Both serotonin and norepinephrine help to deliver messages between nerve cells in your brain and other parts of the body. But having too much or too little of either neurotransmitter can cause physical and psychological symptoms, including depression.
In addition to inhibiting serotonin and norepinephrine reuptake, Cymbalta also enhances dopamine levels within the prefrontal cortex of the brain. Dopamine is believed to play an important role in bodily function, motivation, arousal, and how you experience joy and pleasure.
How long does it take for Cymbalta to work?
Like many antidepressants, it can take some time before the full effects of Cymbalta kick in, especially if it’s your first time using the medication.
In most cases, it can take between four and eight weeks for Cymbalta to improve your depression and anxiety and have a positive effect on your overall mood and outlook.
If you’ve been taking Cymbalta for at least 1-2 months but are not experiencing any benefits or improvement in mood, talk to your provider about changing your dosage or possibly discontinuing the medication. If you stop taking your medication abruptly, you can develop discontinuation syndrome, an uncomfortable set of withdrawal symptoms which can include irritability, anxiety, dizziness, upset stomach, excessive sweating, trouble balancing, sleep changes, tremors, and suicidal thoughts.
Is there a generic for Cymbalta?
Cymbalta is a brand-name prescription medication manufactured by Eli Lilly and Company.
It is also available as a generic prescription medication under the name duloxetine. Both the brand-name and generic forms of the medication are only available by prescription.
It’s important to keep in mind that in order to meet FDA standards, the generic form of any medication must be “bioequivalent” to the brand-name version of the drug. This means that it must have the same active ingredients at the same dosage, and be equally effective at treating the medical condition for which it is intended.
The primary difference between a generic medication and a brand-name medication is that the generic is often sold at a lower price.
Cymbalta can cause side effects. The most common side effects include:
• Abdominal pain
• Change in libido
• Decrease in appetite
• Dry mouth
• Increased sweating
• Weight loss
Serious side effects are less common, but possible. Examples of serious side effects include:
• Easy bruising
• Feelings of lightheadedness or fainting
• Hepatotoxicity (damage to the liver)
• Hyponatremia (low concentration of sodium in the blood)
• Loss of consciousness
• Painful or difficult urination
• Pounding heartbeats or fluttering in the chest
• Serotonin syndrome
• Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
• Vision changes
If you experience any of these more severe side effects, seek care as soon as possible.
Cymbalta is usually taken in delayed-release capsule form because it is well absorbed in this form and can be taken orally with or without food. The recommended starting dose for Cymbalta for the treatment of depression is between 30-40 mg once per day.
When taking any medication, it’s important to follow the instructions on the label exactly as directly and to follow any instructions given by your pharmacist or provider.
Do not split, chew, or crush Cymbalta capsules. It’s also important not to open the delayed-release Cymbalta capsules and mix them with other liquids or foods.
Many medications can have an interaction with Cymbalta, including nonsteroidal anti-inflammatory drugs (NSAIDs), and other prescription and over-the-counter (OTC) medicines as well vitamins and herbal products.
This is why it’s very important to talk to your provider about any drugs or supplements you’re currently taking to avoid possible drug interactions.
Examples of medications that can interact with Cymbalta include:
• MAO Inhibitors
• Rizatriptan (Maxalt)
• St. John’s wort
• Sumatriptan (Imitrex)
• Tramadol (Ultram)
Medication costs can vary depending on the dosage recommended by your provider, your insurance coverage, and the pharmacy from which you purchase your medication.
Keep in mind that shopping for Cymbalta online can help to keep costs low and it can be an easy and convenient way to get your prescription at the lowest price.
Is Cymbalta right for you?
If you’re suffering from depression, anxiety, or chronic pain, Cymbalta may be right for you. Before starting any new medication, talk to a licensed medical provider about your options and whether Cymbalta or another antidepressant medication may be best for you and your symptoms.
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I have many health issues and no health insurance, so I frequently need urgent care. K Health has been my favorite online service so far because you don’t have to do a phone call or video call – it is all text based. As someone with social anxiety this is a wonderful feature. I have used the service twice now and both times I have been helped quickly and efficiently. I recommend this to anyone who needs quick urgent care for a minor illness.Stormy R. | Jun 11 2022
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I can not afford insurance, so I could not afford to see a doctor about my anxiety and panic attacks before finding K Health. I literally hid at home all the time and had massive panic attacks resulting in trips to the ER over basic stuff like grocery shopping. Now I actually look forward to getting out. I’ve developed hobbies that have turned into a home business and actually made a few friends. K Health literally saved me from myself. Thank you!!!Heather C. | May 24 2022
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Easy way to get my anxiety medication from professionals. Their mail option for my meds is cheaper and faster than waiting in line at pharmacies like Walgreens too. I haven’t had to wait longer than 5 mins to talk to a doctor! Awesome!Carissa M. | Feb 15 2022
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I am a homeless disabled 70 yr old who lost my secondary healthcare. I have been able to continue receiving compassionate therapeutic listening to my stressful situation and receive monthly prescriptions of my antidepressants that I have been on since the 1990’s.Margie B. | Oct 22 2021
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I lost my insurance but didn’t want to lose all the progress I made and was at a point of feeling better. I’m able to speak to a psychiatrist once a month and get my prescription refilled that I already know works for me for a low cost.K Health Member | Oct 17 2021
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For my depression/anxiety they were receptive to input on what worked before and helped me find a dose that works.Matthew D. | Oct 06 2021
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Absolutely life changing for me! Thank you for creating a great app to help people like me who cant afford expensive trips to the doctors. Mental health is so important and this makes it so easy to get the meds I need.Bella W. | Sep 09 2021
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Absolutely amazing. They are helping me greatly with my anxiety and stress and panic attacks. Great, great doctors as well.Amanda N. | May 12 2021
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I really like this app. Affordable price and gets what I need ASAP. Just got my refill for my anxiety and it’s been awesome. My life has changed for the better. Recommend to anyone!Keyvon T. | Apr 07 2021