What Is Super Gonorrhea?

By Frank DiVincenzo, MD
Medically reviewed checkmarkMedically reviewed
February 24, 2022

Super gonorrhea, also referred to as super-resistant gonorrhea, is a case of the common sexually transmitted disease (STD) that resists typical treatment from antibiotics.

This type of gonorrhea is referred to as a superbug and is a serious threat to public health.

In this article, we’ll explore what super gonorrhea is, how common it may be, symptoms, and treatment. We’ll also discuss how you should know when to seek medical help, how to get tested, and how to avoid serious complications.

What is Super Gonorrhea?

Super gonorrhea is not more contagious or different symptomatically from other types of gonorrhea.

It is an antimicrobial-resistant strain of the common STD that is becoming more common due to the overuse of the antibiotics used to treat it, such as injectable ceftriaxone with oral azithromycin.

Azithromycin, in particular, is increasing in frequency of use, which can contribute to resistance.

While azithromycin is not shown to be effective at treating COVID-19, studies have looked at it for this purpose.

A spokesman from the World Health Organization (WHO) told a reporter from The Sun that overuse of azithromycin for COVID-19 was directly leading to drug-resistant strains of gonorrhea.

While additional reporting has found that this link is not as dire or imminent as it sounds, the fact remains that antibiotics continue to be overused. The more frequently antibiotics are used ineffectively, the more likely it is that bacteria will be able to evolve and resist more forms of treatment.

Gonorrhea is the second most common STD, affecting more than 616,000 Americans according to the CDC. Rates of gonorrhea have skyrocketed 92% in the last 10 years.

While gonorrhea is a common sexually transmitted infection, particularly in young adults and men who have sex with other men, the disease is not always simple to treat. It can be transmitted via vaginal, anal, or oral sex and is highly contagious.

Gonorrhea is caused by the bacteria N. gonorrhoeae, which has a history of becoming resistant to antibiotics.

Because new antibiotic treatments are not yet available, super gonorrhea cases may become more common, elevating an STD that was formerly simple to treat to a complex medical problem that could require hospitalization and intravenous antibiotics.

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How Is Super Gonorrhea Different From Standard Gonorrhea?

While the symptoms of gonorrhea and super gonorrhea are the same, the primary way that they are different is that super gonorrhea symptoms will not resolve after the typical course of treatment.

Usually, symptoms of gonorrhea will resolve within seven days of treatment.

If they do not, you need to inform your healthcare provider as you may have super-resistant gonorrhea or may have a co-occurring infection, such as chlamydia.

How Common is Super Gonorrhea?

Super gonorrhea is still rare. The CDC has not yet received reports of super gonorrhea in the U.S. But as rates of gonorrhea and other STDs continue to rise, it will become more common.

What Causes Super Gonorrhea?

According to the World Health Organization, there are five primary reasons for gonorrhea becoming super-resistant.

  • Frequent, unrestricted use of antibiotics
  • Inappropriate selection of antibiotics to treat  specific infections
  • Poor antibiotic quality
  • Genetic mutations
  • Gonorrhea infections outside of the genitals (particularly the throat)

The risk factors for contracting gonorrhea include:

  • Having sexual contact with a new partner or having more than one sexual partner
  • Having sex with someone who has multiple sexual partners
  • Having a history of sexually transmitted infections
  • Not using condoms when not in a monogamous relationship
  • Sex work

Men who have sex with men may also be at increased risk for gonorrhea, as well as people under age 25, and African Americans.

Gonorrhea typically infects the mucus membranes of male and female reproductive tracts. In people with penises, it affects the urethra, with or without symptoms.

For those with vaginas, it can infect the urethra, cervix, uterus, and fallopian tubes. Gonorrhea may also present as anal, throat, or eye infections.

Gonorrhea can be passed to an infant during childbirth.

Safe sex practices are the best way to decrease the risk of contracting gonorrhea.

This means using latex condoms, avoiding any unprotected sexual contact outside of a mutually monogamous relationship, and getting tested regularly if you do have multiple partners.

How to Know if You Have Super Gonorrhea

The symptoms of super gonorrhea are not different from normal gonorrhea infections.

In many cases, it causes no symptoms at all. However, if you are treated for gonorrhea and your symptoms do not improve within seven days, you should check with your doctor.

Super gonorrhea resists common treatment and may continue to cause symptoms even after antibiotics.

Symptoms of Super Gonorrhea

Gonorrhea does not always cause symptoms, and when it does, they may be mild enough not to cause concern.

However, if you have had unprotected sexual activity with a new or multiple partners and have any of the following symptoms, you should seek testing and medical care to ensure that you get proper treatment.

Symptoms of gonorrhea may include:

When gonorrhea is left untreated, it can lead to prostate and testicular problems in men. In women, it can lead to pelvic inflammatory disease, which could cause problems with fertility and future pregnancy.

It may also increase the risk of ectopic pregnancy, a medical emergency. Gonorrhea can also increase the risk of transmitting or acquiring HIV.

How to Get Tested

If you have had contact with someone who has tested positive for gonorrhea, or you are showing signs or symptoms, contact your medical provider. Testing for gonorrhea can easily be done in a healthcare provider’s office.

Gonorrhea testing is done via urine specimen or via specimen collection from the urethra (for those with a penis) or the cervix or vagina. The FDA has also approved tests for oral or rectal infections.

Treatment of Super Gonorrhea

Gonorrhea is typically treated with an intramuscular injection of ceftriaxone. This is sometimes paired with a course of doxycycline or azithromycin.

Super-resistant gonorrhea will not respond to this first-line treatment.

While no cases have yet been identified in the U.S., in other countries, when conventional treatment fails, super gonorrhea has been treated with intravenous antibiotics that are typically reserved for serious, life-threatening infections.

Because super gonorrhea has not been found in the U.S. yet, the CDC’s recommended protocol of ceftriaxone is still standard care.

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What Happens if It’s Not Treated Effectively?

If gonorrhea is not treated effectively, it can lead to serious, long-term, permanent health complications, including:

  • Pelvic inflammatory disease
  • Ectopic pregnancy
  • Infertility in men and women
  • Pelvic and abdominal pain
  • Increased risk of contracting HIV
  • bacterial infection of blood or joints that may be life-threatening

When to See a Doctor

If you have symptoms that are associated with gonorrhea, see your doctor.

If you don’t have symptoms but have multiple sexual partners or are a man who has sex with other men, you should get routine STD screenings from your health care provider.

Gonorrhea requires a medical diagnosis.

To avoid complications, it needs to be treated in a timely manner. There is no natural way to treat gonorrhea. Because it is a bacterial infection, it requires antibiotics.

Gonorrhea may also co-occur with other STDs or sexually transmitted infections (STI). Regular healthcare screenings are important, especially if you are sexually active, under the age of 25, or have multiple partners.

How K Health Can Help

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Frequently Asked Questions

How do you get super gonorrhea?
Super gonorrhea is transmitted the same as any other STD. Super gonorrhea occurs when you contract a strain of bacteria that is resistant to common antibiotic treatment methods. As of right now, super gonorrhea has not been found in the United States.
Can you get rid of antibiotic-resistant gonorrhea?
Antibiotic-resistant gonorrhea is treated with antibiotics that do not show resistance, longer courses of antibiotics, or a combination of antibiotic drugs. Serious cases of super-resistant gonorrhea are treated in a hospital with IV antibiotics.
K Health articles are all written and reviewed by MDs, PhDs, NPs, or PharmDs and are for informational purposes only. This information does not constitute and should not be relied on for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment.

K Health has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. We avoid using tertiary references.

Frank DiVincenzo, MD

Dr. Frank DiVincenzo has been a physician with K Health since 2020. He grew up near Chicago, Illinois, but left the big city to go to college and then attend graduate school in Missouri. He received a Bachelor of Science in Mathematics and a Master of Science in Microbiology before graduating from the University of Missouri–Columbia School of Medicine.