OMEPRAZOLE (oh ME pray zol) is used to treat heartburn, stomach ulcers, reflux disease, or other conditions that cause too much stomach acid. It works by reducing the amount of acid in the stomach. It belongs to a group of medications called PPIs.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
Have had heartburn for over 3 months
Have heartburn with dizziness, lightheadedness or sweating
Low levels of calcium, magnesium, or potassium in the blood
Unexplained weight loss
Vomiting with blood
An unusual or allergic reaction to omeprazole, other medications, foods, dyes, or preservatives
Pregnant or trying to get pregnant
How should I use this medication?
Take this medication by mouth with a glass of water. Follow the directions on the product label. Do not cut, crush or chew this medication. Swallow the tablets whole. Take this medication on an empty stomach, at least 30 minutes before breakfast. Take your medication at regular intervals. Do not take it more often than directed.
Talk to your care team about the use of this medication in children. Special care may be needed.
What if I miss a dose?
If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.
What may interact with this medication?
Do not take this medication with any of the following:
This medication may also interact with the following:
Antifungals like itraconazole, ketoconazole, and voriconazole
Certain antivirals for HIV or hepatitis
Certain medications that treat or prevent blood clots like warfarin
Medications for anxiety, panic, and sleep like diazepam
Medications for seizures like carbamazepine, phenobarbital, phenytoin
St. John's wort
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
Kidney injury—decrease in the amount of urine, swelling of the ankles, hands, or feet
Low magnesium level—muscle pain or cramps, unusual weakness, fatigue, fast or irregular heartbeat, tremors
Low vitamin B12 level—pain, tingling, or numbness in the hands or feet, muscle weakness, dizziness, confusion, difficulty concentrating
Rash on the cheeks or arms that gets worse in the sun
Redness, blistering, peeling, or loosening of the skin, including inside the mouth
Severe diarrhea, fever
Unusual bleeding or bruising
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
What should I watch for while using this medication?
It can take several days before your stomach pain gets better. Check with your care team if your condition does not start to get better, or if it gets worse.
Do not treat diarrhea with over the counter products. Contact your care team if you have diarrhea that lasts more than 2 days or if it is severe and watery.
You may need blood work done while you are taking this medication.
Using this medication for a long time may weaken your bones. The risk of bone fractures may be increased. Talk to your care team about your bone health.
Using this medication for a long time may cause growths (polyps) in the stomach. They usually don't cause any symptoms. They are usually not cancerous. Contact your care team if you notice pain or tenderness when you press your stomach, have nausea, or see bloody or black, tar-like stools.
This medication may cause a decrease in vitamin B12. You should make sure that you get enough vitamin B12 while you are taking this medication. Discuss the foods you eat and the vitamins you take with your care team.
Where should I keep my medication?
Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from light and moisture. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or expired:
Take the medication to a medication take-back program. Check with your pharmacy or law enforcement to find a location.
If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put in the trash, empty the medication out of the container. Mix the medication with cat litter, dirt, coffee grounds, or other unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
K Health articles are all written and reviewed by MDs, PhDs, NPs, or PharmDs and are for informational purposes only. This information does not constitute and should not be relied on for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment.
This information is educational only and should not be construed as specific instructions for individual patients nor as a substitute for medical advice, diagnosis or treatment. Talk to your health care provider or pharmacist about the information and instructions. K Health assumes no liability for any use or reliance on this information.